Does this acidity cause any clinical problems after the tooth is restored?
No. The pH of ED Primer increases as it dissolves into the tooth, yet is neutralized by calcium ions. When composites and bonding agents polymerize they are inert; therefore, they do not cause pulpal irritation.
Irritation to the pulp occurs when the dentin is not completely sealed. It does not result from a reaction to the composite or bonding agent.