After Kuraray introduced the first adhesive monomer in dental history by inventing the phosphate monomer Phenyl-P in 1976, its molecular structure was improved in 1981 by creating a molecule with greater adhesive capability to the tooth structure and an affinity for metal. The result of this development work was the MDP monomer (10-Methacryloyloxydecyl dihydrogen phosphate), which convinced users by its special monomer structure: This phosphate monomer was extremely effective for enamel, dentin and on metal alloys. Consequently, PANAVIA, including the MDP monomer, was introduced as a high-performance adhesive resin cement for the cementation to tooth structure and to metals.
The impressive success of PANAVIA encouraged Kuraray to integrate the MDP monomer into other bonding systems as well as to obtain a high degree of adhesion to tooth substrate from the formation of a chemical bonding.